BENIGN SYMMETRIC LIPOMATOSIS - LAUNOIS-BENSAUDE
SYNDROME OR MADELUNG'S DISEASE -
D. Gogalniceanu , Daniela Trandafir, Violeta
Department of Oral and Maxillo-Facial Surgery
University of Medicine and Pharmacy „Gr.T. Popa” Iasi,
Jurnalul de chirurgie 2005; 1 (2):190-195
Full text: Format
Benign symmetric lipomatosis (BSL) is a rare proliferative disorder
of the adipose tissue, characterized by symmetrical fat deposits,
predominantly in the neck and shoulder area, upper back and arms.
A classification in three types according to the distribution of
the pathological fatty was proposed by Donhauser (1991): type 1 (localized
cervical fat proliferation); type 2 (pseudoathletic type); type 3
METHODS: This study contains the analyse of a lot of ten patients
with BSL, which were treated in our department between 1994 - 2004.
The followed parameters were: sex, age, heredo-collateral antecedents,
associated organic diseases, the motivation of medical addressability,
the sites of first lesions, the length of evolution before the admission,
methods for diagnosis, number of surgical sessions necessary to extirpation
of fat deposits, the results of the periodic follow-up examination.
RESULTS: The followed patients with BSL were treated by surgery
(extirpation of the inaesthetical cervical fat masses): one surgical
session (8 cases); two sessions (2 cases). The follow-up examinations
(clinical and laboratory tests) were accomplished at 3 months, 6 months,
1 year and 3 years (meanly regarding local recurrence). 8 cases: good
results; 1 case: the associate peripheral neuropathy due to alcohol
abuse made worse; 1 case: in course of pursuit. Recurrence at the
site of surgery was not detected in any of the follow-up subjects.
All of the patients were satisfied with the surgical result.
CONCLUSIONS: The elective treatment in BSL is surgical, by
extirpation of the lipomatous masses; a satisfactory, lasting result
can be expected only after the most radical possible extirpation (not
only for cosmetic intentions ). Our study doesn't take down any local
recurrence after the wide extirpations of the cervical disfigurement
fat deposits (sometimes was necessary concomitent extirpation of the
infiltrative structures - parotidectomy or submaxillectomy ).
KEYWORDS: MADELUNG' S DISEASE, MULTIPLE SYMMETRIC LIPOMATOSIS,
BENIGN SYMMETRIC LIPOMATOSIS, SURGICAL TREATMENT IN BSL.
Correspondence: Prof. Dr. D. Gogalniceanu, Clinic Oral and
Maxillo-Facial Surgery, „St. Spiridon” University Hospital
Iasi, Independentei Street, no. 1, 700111, Iasi, Romania